Because of the higher boiling point, dibenzylcarbonate (DBnC) allows much simpler conditions with respect to DMC: reactions can be performed at atmospheric pressure in normal glass apparatus. This fact, along with the peculiar high selectivity observed (at almost complete conversion) facilitates workup and separation of the mono-C-alkyl product. DBnC can be used to benzylate phenylacetoni-trile, benzyl phenylacetate, and phenol, in refluxing DMF with a K2CO3 catalyst (Scheme 4.22).42 The mechanism is analogous to the one sketched out for DMC (Scheme 4.10), and involves consecutive carboxybenzylation/benzylation steps.
Was this article helpful?
Global warming is a huge problem which will significantly affect every country in the world. Many people all over the world are trying to do whatever they can to help combat the effects of global warming. One of the ways that people can fight global warming is to reduce their dependence on non-renewable energy sources like oil and petroleum based products.