Incubation period weeks

Period of communicability In the asymptomatic case, infection can continue for a considerable period of time.

Occurrence and distribution NGU is more common than gonorrhoea and is found all over the world with high levels in the sexually promiscuous.

Control and prevention is the same as for gonorrhoea and syphilis (see above).

Treatment is with azithromycin 1 g orally in a single dose, doxycycline 100 mg orally twice daily for 7 days, erythromycin 500 mg orally four times a day for 7 days or tetracycline 500 mg orally four times daily for 7 days. Sexual intercourse must be avoided until both partners are free of signs. While cases of gonorrhoea should always be treated for NGU, if gonorrhoea has been excluded, then cases of NGU do not also need to be treated for gonorrhoea. If a low-grade offensive discharge with some staining persists in the female, or irritation in the male, this is probably Trichomonas infection, which is effectively treated with metronidazole 2 g orally or tinidazole 2 g orally in a single dose.

Surveillance Several STIs can occur together, hence NGU is an indicator of possible syphilis and gonorrhoea, which should always be looked for.

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